In the pre-Hispanic period, it was an important ceremonial center of the Purhépechas. On his arrival Don Vasco de Quiroga transferred the bishopric from Tzintzuntzan to Patzcuaro, converting it into the capital of Michoacan (1539-1580). It is one of the typical most beautiful towns of America. Its magnificent constructions of adobe and tile, monumental temples, and the spectacular Vasco de Quiroga Square converts it into one of the main tourist centers of the Mexican Republic.

The outskirts of the Patzcuaro Lake and its Islands are found inhabited by the indigenous community that conserves great part of its costumes and traditions. Its fishermen are worldwide known, due to the butterfly-form nets, that they use to fish the delicious white fish which is in extinction at the present time.